Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
| ▸ | USP4 | Q13107 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11093147 | 0.83 | IDO1 (0.47) | KDM4EALDH1A1IDO1MAPTMEN1 | |
| SCHEMBL11093143 | 0.83 | MAPT (0.37) | KDM4EALDH1A1GAAIDO1USP2 | |
| SCHEMBL10869194 | 0.79 | SIRT1 (0.55) | KDM4EALDH1A1GAAIRAK4SIRT1 | |
| SCHEMBL1004596 | 0.75 | KDM4E (0.63) | KDM4EALDH1A1GAAIRAK4IKBKB | |
| SCHEMBL11089219 | 0.75 | ALDH1A1 (0.42) | ALDH1A1USP2USP8USP5USP4 | |
| SCHEMBL7404678 | 0.73 | KDM4E (0.61) | KDM4EALDH1A1GAAIRAK4IKBKB | |
| Potassium SCHEMBL7404680 | 0.73 | KDM4E (0.61) | KDM4EALDH1A1GAAIRAK4IKBKB | |
| SCHEMBL11095399 | 0.73 | PARP1 (0.37) | KDM4EALDH1A1USP2USP8USP5 | |
| SCHEMBL11093483 | 0.73 | GABRA1 (0.43) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL11092051 | 0.73 | ALDH1A1 (0.46) | KDM4EALDH1A1GAAHPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018100-B1 | SUBSTITUTED AROMATIC BIOLOGICALLY ACTIVE COMPOUND, A PROCESS FOR ITS PREPARATION AND ITS USE AS BIOCIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-18 | — | — | EP | disclosed |
| EP-0018100-A2 | Substituted aromatic biologically active compound, a process for its preparation and its use as biocide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-10-29 | — | — | EP | disclosed |