Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083426 | 0.91 | ALDH1A1 (0.46) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11092528 | 0.85 | ALDH1A1 (0.51) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11093455 | 0.76 | HTT (0.40) | HTTALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL11092417 | 0.76 | PDE5A (0.43) | ALDH1A1KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL11087620 | 0.75 | KDM4E (0.50) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11032375 | 0.75 | KDM4E (0.54) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10339705 | 0.75 | KDM4E (0.50) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8880504 | 0.72 | HTT (1.00) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11112233 | 0.72 | KDM4E (0.46) | HTTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11082703 | 0.71 | KDM4E (0.61) | HTTALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58180486-A | — | — | None | — | — | JP | disclosed |
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |
| JP-S58180486-A | 5-PHENYLOXY-1-PHENYL-1H-PYRAZOLO(3,4-B)PYRAZINE DERIVATIVE | LION CORP | 1983-10-21 | — | — | JP | disclosed |