Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | SLC2A2 | P11168 | 2/20 | 0.40 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087620 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL11032375 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL10339705 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL11092528 | 0.74 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL11082703 | 0.72 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL11090510 | 0.72 | PDGFRB (0.55) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL11094259 | 0.72 | HTT (0.55) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL29387290 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL18366927 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL11083426 | 0.70 | ALDH1A1 (0.46) | KDM4EALDH1A1KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460773-A | ANTITUMOR AGENTS, VIRICIDES | LION CORPORATION (JP) | 1984-07-17 | — | — | US | disclosed |