Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11032375 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11087620 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11092528 | 0.78 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11112233 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11082703 | 0.75 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11090510 | 0.75 | PDGFRB (0.55) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11094259 | 0.75 | HTT (0.55) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11087354 | 0.73 | NPC1 (0.53) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11089283 | 0.72 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10KMT2ATSHR | |
| SCHEMBL11130485 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2240084-A | — | — | None | — | — | JP | disclosed |
| JP-H02240084-A | 1,5-DISUBSTITUTED-1H-PYRAZOLO(3,4-B)-PYRAZINE DERIVATIVE AND ANTITUMOR AGENT CONTAINING THE SAME COMPOUND | LION CORP | 1990-09-25 | — | — | JP | disclosed |