Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093049 | 0.85 | L3MBTL1 (0.42) | — | |
| Maleic Acid SCHEMBL11093657 | 0.82 | MAPT (0.43) | PDE4BPIK3CA | |
| Fumaric Acid SCHEMBL11093658 | 0.82 | MAPT (0.43) | PDE4BPIK3CA | |
| SCHEMBL11094339 | 0.80 | NPY5R (0.40) | — | |
| SCHEMBL11095517 | 0.80 | AKT1 (0.43) | PDE4BPIK3CA | |
| Maleic Acid SCHEMBL11094370 | 0.79 | P2RY1 (0.40) | PDE4B | |
| Fumaric Acid SCHEMBL11094374 | 0.79 | P2RY1 (0.40) | PDE4B | |
| SCHEMBL11139159 | 0.78 | PDE4B (0.38) | PDE4B | |
| SCHEMBL11139157 | 0.78 | PDE4B (0.38) | PDE4B | |
| SCHEMBL11093912 | 0.77 | OTUD7B (0.42) | PDE4BPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209625-A | Spiro[indoline-3,4'-piperidine]s | AMERICAN HOECHST CORPORATION (US) | 1980-06-24 | — | — | US | claimed |
| US-4477667-A | Spiro[indoline-3,4'-piperidine]s and related compounds | AMERICAN HOECHST CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4307235-A | Spiro[indoline-3,4'-piperidine]s | AMERICAN HOECHST CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |