Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | DDX3X | O00571 | 2/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215471 | 0.86 | SMN1; SMN2 (0.67) | MAPTSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL11735282 | 0.85 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL27964933 | 0.83 | KMT2A (0.69) | MAPTSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL3207627 | 0.80 | KMT2A (0.78) | MAPTSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL3205682 | 0.80 | SMN1; SMN2 (0.69) | MAPTHSP90AA1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3972854 | 0.80 | KMT2A (0.63) | MAPTHSP90AA1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL31185157 | 0.79 | SMN1; SMN2 (0.68) | MAPTSMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL10346279 | 0.78 | PDK1 (0.60) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6159935 | 0.78 | MAPT (0.68) | MAPTHSP90AA1GPR55SMN1; SMN2POLB | |
| SCHEMBL10692848 | 0.78 | KMT2A (0.66) | MAPTSMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041170-B1 | 3-NITRO-PIVALOYL-ACETANILIDES, PROCESSES FOR THEIR PREPARATION AND THEIR UTILIZATION | BAYER AG (DE) | 1984-07-25 | — | — | EP | claimed |
| US-4370499-A | CHEMICAL INTERMEDIATES FOR COLOR PHOTOGRAPHY | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-25 | — | — | US | claimed |
| EP-0041170-A1 | 3-Nitro-pivaloyl-acetanilides, processes for their preparation and their utilization | BAYER AG (DE) | 1981-12-09 | — | — | EP | claimed |
| EP-0041170-B1 | 3-NITRO-PIVALOYL-ACETANILIDES, PROCESSES FOR THEIR PREPARATION AND THEIR UTILIZATION | BAYER AG (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4370499-A | CHEMICAL INTERMEDIATES FOR COLOR PHOTOGRAPHY | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4356258-A | AN ACYLACETANILIDE DERIVATIVE; IMAGE PRESERVATION | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1982-10-26 | — | — | US | disclosed |
| EP-0041170-A1 | 3-Nitro-pivaloyl-acetanilides, processes for their preparation and their utilization | BAYER AG (DE) | 1981-12-09 | — | — | EP | disclosed |
| EP-0041171-A1 | 2-Chloro-5-nitro-phenyl isocyanate, process for its preparation and its use | BAYER AG (DE) | 1981-12-09 | — | — | EP | disclosed |