Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481740 | 0.90 | CAMK2A (0.55) | CXCL8ABCB11LMNAPTGS1ADORA1 | |
| SCHEMBL11092450 | 0.89 | CXCL8 (0.50) | CXCL8ABCB11LMNAPTGS1ADORA1 | |
| SCHEMBL11092305 | 0.89 | CXCL8 (0.75) | CXCL8ABCB11LMNAPTGS1ADORA1 | |
| SCHEMBL11084311 | 0.89 | CXCL8 (0.75) | CXCL8ABCB11PTGS1PTGS2CHRM1 | |
| SCHEMBL11089469 | 0.88 | CXCL8 (0.60) | CXCL8ABCB11LMNAPTGS1ADORA1 | |
| SCHEMBL11094218 | 0.88 | TDP1 (0.59) | CXCL8CHRM1AKR1B1TDP1HPGD | |
| SCHEMBL16397224 | 0.86 | HSD17B10 (0.50) | CXCL8ABCB11LMNAPTGS1ADORA1 | |
| SCHEMBL22654316 | 0.85 | LMNA (0.57) | CXCL8ABCB11LMNAPTGS1ADORA1 | |
| SCHEMBL11089474 | 0.84 | CHRM1 (0.76) | CXCL8LMNACHRM1TDP1CYP2C9 | |
| SCHEMBL7583347 | 0.84 | AKR1B1 (0.58) | CXCL8ABCB11LMNAPTGS1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |