Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.38 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112933 | 0.85 | PGR (0.49) | SLC6A3SMN1; SMN2CACNB4CACNA1ACACNA1G | |
| SCHEMBL24112226 | 0.85 | PGR (0.49) | SLC6A3SMN1; SMN2CACNB4CACNA1ACACNA1G | |
| SCHEMBL11093677 | 0.82 | CACNB4 (0.36) | SLC6A2SLC6A4SLC6A3HTR1ASMN1; SMN2 | |
| SCHEMBL11123362 | 0.71 | HPGD (0.38) | SLC6A2SLC6A4SLC6A3HTR1ASMN1; SMN2 | |
| SCHEMBL11090819 | 0.71 | HTR1A (0.35) | SLC6A2SLC6A4HTR1ASMN1; SMN2CACNB4 | |
| SCHEMBL11094086 | 0.70 | HTR1A (0.34) | HTR1AMEN1USP2KMT2AHTR1D | |
| SCHEMBL24112725 | 0.70 | ALDH1A1 (0.43) | PGRDAOMEN1KMT2AHTR2C | |
| SCHEMBL24112230 | 0.70 | ALDH1A1 (0.43) | PGRDAOMEN1KMT2AHTR2C | |
| SCHEMBL4408041 | 0.70 | PGR (0.40) | HTR1ASMN1; SMN2CACNB4CACNA1ACACNA1G | |
| SCHEMBL20939667 | 0.68 | PDE7A (0.40) | SMN1; SMN2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472433-A | Phenoxyphenyl acetic acids and their medicinal use | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0008226-B1 | PHENYL-ALKANOIC ACID DERIVATIVES, THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-02 | — | — | EP | disclosed |
| EP-0008226-A2 | Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-20 | — | — | EP | disclosed |