Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.67 |
| ▸ | GSK3B | P49841 | 2/20 | 0.67 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203931 | 0.81 | GSK3B (1.00) | PTPN1GSK3BMMP1HDAC1HDAC8 | |
| SCHEMBL22105381 | 0.78 | MMP1 (0.62) | PTPN1GSK3BMMP1HDAC1HDAC8 | |
| Formaldehyde SCHEMBL28094444 | 0.78 | GSK3B (0.92) | PTPN1GSK3BMMP1HDAC1HDAC8 | |
| SCHEMBL23014264 | 0.77 | PTPN1 (0.57) | PTPN1GSK3BMMP1HSD11B1PDPK1 | |
| SCHEMBL29987081 | 0.77 | PTPN1 (0.75) | PTPN1GSK3BMMP1HDAC1HDAC8 | |
| SCHEMBL23014202 | 0.76 | ALDH1A1 (0.56) | PTPN1GSK3BMMP1ALDH1A1MAPT | |
| SCHEMBL31557731 | 0.75 | PTPN1 (0.75) | PTPN1GSK3BMMP1HDAC1HDAC8 | |
| SCHEMBL13724828 | 0.74 | GSK3B (0.61) | PTPN1GSK3BMMP1CES2CES1 | |
| SCHEMBL19655646 | 0.74 | PTPN1 (0.49) | PTPN1GSK3BMMP1HDAC1HDAC8 | |
| SCHEMBL23014091 | 0.73 | LSS (0.52) | PTPN1GSK3BMMP1HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443616-A | Production of 3-pyrrolin-2-ones | THE PURDUE FREDERICK COMPANY (US) | 1984-04-17 | — | — | US | disclosed |