Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.53 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329567 | 0.85 | PTPN1 (0.58) | GSK3BPTPN1CES2CES1LSS | |
| SCHEMBL13724678 | 0.82 | CES2 (0.57) | GSK3BPTPN1CES2CES1MAPK14 | |
| SCHEMBL4102813 | 0.81 | NAMPT (0.60) | GSK3BPTPN1MLYCDMCHR1EPHX2 | |
| SCHEMBL4187911 | 0.81 | CES2 (0.55) | GSK3BPTPN1CES2CES1MAPK14 | |
| SCHEMBL10264321 | 0.81 | LSS (0.56) | GSK3BPTPN1CES2CES1MAPK14 | |
| SCHEMBL5124494 | 0.79 | KDM4E (0.62) | GSK3BPTPN1CES2CES1MAPK14 | |
| SCHEMBL28968592 | 0.78 | LSS (0.54) | GSK3BPTPN1CES2CES1MAPK14 | |
| SCHEMBL6358316 | 0.78 | ALDH1A1 (0.69) | CES2CES1LSSMLYCDMCHR1 | |
| SCHEMBL28800304 | 0.78 | CES2 (0.61) | GSK3BPTPN1CES2CES1EPHX2 | |
| SCHEMBL182755 | 0.78 | CES2 (0.61) | GSK3BPTPN1CES2CES1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197201-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197201-A1 | FLUOROSURFACTANTS | CBR3, SCO2, FPR3 | GSK3B 4138/4885PTPN1 2436/4885CES2 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.