Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371812 | 0.85 | TSHR (0.52) | TSHRCYP3A4ALDH1A1TDP1GAA | |
| SCHEMBL9559517 | 0.84 | ALDH1A1 (0.58) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL29872530 | 0.84 | ALDH1A1 (0.58) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL938653 | 0.82 | TSHR (0.57) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL28740174 | 0.80 | ALDH1A1 (0.54) | TSHRCYP3A4ALDH1A1TDP1GPR35 | |
| SCHEMBL2056619 | 0.80 | TSHR (0.55) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL823521 | 0.80 | TSHR (0.55) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL3683680 | 0.78 | TSHR (0.55) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL2763390 | 0.78 | GPR35 (0.52) | TSHRCYP3A4ALDH1A1TDP1GAA | |
| SCHEMBL23035409 | 0.77 | TSHR (0.52) | TSHRCYP3A4ALDH1A1TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |