Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28659258 | 0.85 | TSHR (0.52) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL10686251 | 0.84 | ALDH1A1 (0.58) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL22288521 | 0.84 | MEN1 (0.46) | TSHRCYP3A4ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL938653 | 0.82 | TSHR (0.57) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL823521 | 0.80 | TSHR (0.55) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL23035421 | 0.80 | ALDH1A1 (0.42) | TSHRCYP3A4ALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL2056619 | 0.80 | TSHR (0.55) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL11095255 | 0.77 | TSHR (0.52) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL11882257 | 0.77 | TSHR (0.52) | TSHRCYP3A4ALDH1A1TDP1RECQL | |
| SCHEMBL1896028 | 0.77 | GAA (0.52) | TSHRCYP3A4ALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112368268-B | Phenyl bitriazole MLL1-WDR5 protein-protein interaction inhibitor | 中国药科大学 | 2025-03-04 | — | — | CN | disclosed |
| EP-3786157-B1 | PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | UNIV CHINA PHARMA (CN) | 2024-08-07 | — | — | EP | disclosed |
| US-12054478-B2 | Compositions and methods for inhibiting phenyl triazole MLL1-WDR5 protein-protein interaction | HUYABIO INTERNATIONAL, LLC (US) | 2024-08-06 | — | — | US | disclosed |
| US-20230098016-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-03-30 | — | — | US | disclosed |
| US-11479545-B2 | Compositions and methods for inhibiting phenyl triazole MLL1-WDR5 protein-protein interaction | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2022-10-25 | — | — | US | disclosed |
| US-20210139466-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2021-05-13 | — | — | US | disclosed |
| EP-3786157-A1 | PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | China Pharmaceutical University (CN) | 2021-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139466-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION | WDR5, MLLT1, WDR1 | TSHR 4658/4885CYP3A4 2672/4885ALDH1A1 3515/4885 |
| US-12054478-B2 | Compositions and methods for inhibiting phenyl triazole MLL1-WDR5 protein-protein interaction | WDR5, MLLT1, WDR1 | TSHR 4658/4885CYP3A4 2672/4885ALDH1A1 3515/4885 |
| US-20230098016-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PHENYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION | WDR5, MLLT1, WDR1 | TSHR 4658/4885CYP3A4 2672/4885ALDH1A1 3515/4885 |
| US-11479545-B2 | Compositions and methods for inhibiting phenyl triazole MLL1-WDR5 protein-protein interaction | WDR5, MLLT1, WDR1 | TSHR 4658/4885CYP3A4 2672/4885ALDH1A1 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.