SCHEMBL11096112

SCHEMBL11096112

CCOc1cc(OCC)c2cc(C(=O)c3cc4ccccc4o3)c(=O)oc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.54
ALDH1A1 P00352 7/20 0.53
RAB9A P51151 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
NPC1 O15118 3/20 0.52
LMNA P02545 2/20 0.48
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
GAA P10253 1/20 0.45
KDM4E B2RXH2 6/20 0.45
FLT3 P36888 1/20 0.45
TSHR P16473 2/20 0.44
MEN1 O00255 1/20 0.44
MAPK1 P28482 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MAOB P27338 3/20 0.44
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4567099 0.90 POLB (0.54) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL6985459 0.86 POLB (0.51) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL194000 0.84 ALDH1A1 (0.52) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL6838345 0.84 ALDH1A1 (0.51) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL52081 0.84 ALDH1A1 (0.68) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL11219985 0.80 RAB9A (0.49) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL29253118 0.78 ALDH1A1 (0.62) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL10703662 0.76 FLT3 (0.71) ALDH1A1RAB9ASMN1; SMN2NPC1LMNA
SCHEMBL11564602 0.76 ALDH1A1 (0.53) POLBALDH1A1RAB9ASMN1; SMN2NPC1
SCHEMBL4567092 0.76 NPC1 (0.59) POLBALDH1A1RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US claimed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
US-20160177453-A1 METHOD OF PHOTOPOLYMERIZING OF ACRYLATES QUALEX INC. 2016-06-23 US disclosed
US-9365658-B2 Method of photocuring acrylate compositions EASTMAN KODAK COMPANY (US) 2016-06-14 US disclosed
US-20150024141-A1 METHOD OF PHOTOCURING ACRYLATE COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2015-01-22 US disclosed
EP-2640755-B1 PHOTOINITIATOR COMPOSITIONS EASTMAN KODAK CO (US) 2014-12-17 EP disclosed
US-20140216283-A1 METHOD OF FLEXOGRAPHIC PATTERNING USING PHOTOCURABLE COMPOSITION FAR EAST DEVELOPMENT LTD. 2014-08-07 US disclosed
US-8399533-B2 Photocurable compositions containing N-oxyazinium salt photoinitiators EASTMAN KODAK COMPANY (US) 2013-03-19 US disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP disclosed