Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838345 | 0.85 | ALDH1A1 (0.51) | RAB9AHPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8376236 | 0.84 | HPGD (0.53) | RAB9AHPGDNPC1TSHRALDH1A1 | |
| SCHEMBL52081 | 0.82 | ALDH1A1 (0.68) | RAB9AHPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11096112 | 0.80 | POLB (0.54) | RAB9AHPGDNPC1TSHRALDH1A1 | |
| SCHEMBL194000 | 0.79 | ALDH1A1 (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11564602 | 0.77 | ALDH1A1 (0.53) | RAB9ANPC1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL11563889 | 0.76 | ALDH1A1 (0.52) | RAB9AHPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29253118 | 0.76 | ALDH1A1 (0.62) | RAB9AHPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL52567 | 0.73 | ALDH1A1 (0.49) | RAB9AHPGDTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6836185 | 0.72 | MAOB (0.49) | RAB9AHPGDNPC1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289844-A | 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED | EASTMAN KODAK COMPANY (US) | 1981-09-15 | — | — | US | claimed |
| EP-0022188-A2 | Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-01-14 | — | — | EP | claimed |
| US-4366228-A | 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED | EASTMAN KODAK COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| US-4289844-A | 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED | EASTMAN KODAK COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0022188-A2 | Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1981-01-14 | — | — | EP | disclosed |