Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.58 |
| ▸ | GSK3A | P49840 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1722780 | 0.77 | GSK3B (0.71) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL15354264 | 0.73 | GSK3B (1.00) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL5199351 | 0.71 | GSK3B (0.71) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL11104133 | 0.71 | GSK3B (0.53) | GSK3BGSK3ALMNAALDH1A1KDM4E | |
| SCHEMBL3763112 | 0.69 | MAPT (0.54) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL11714057 | 0.69 | MAPT (0.54) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL10523507 | 0.68 | TP53 (0.47) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL30976973 | 0.68 | APEX1 (0.63) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL11791224 | 0.68 | PGR (0.64) | GSK3BGSK3ALMNATSHRALDH1A1 | |
| SCHEMBL11712403 | 0.67 | FABP4 (0.54) | GSK3BGSK3ALMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044420-B1 | HYDROXYALKYL-1,2,4-TRIAZOLIDINE-3,5-DIONES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| US-4377694-A | CROSSLINKER, ACTIVATOR FOR POLYESTERS, POLYETHERS, OR POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0044420-A1 | Hydroxyalkyl-1,2,4-triazolidine-3,5-diones and process for their preparation | BAYER AG (DE) | 1982-01-27 | — | — | EP | disclosed |