Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11624948 | 0.84 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL5158239 | 0.83 | MAPT (0.59) | ALDH1A1KDM4EHPGDHTTHSD17B10 | |
| SCHEMBL10880965 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL10889856 | 0.80 | MEN1 (0.78) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL29372498 | 0.80 | POLB (0.72) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL1344307 | 0.80 | POLB (0.72) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL30516994 | 0.80 | POLB (0.72) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL24891376 | 0.80 | MAPT (0.64) | ALDH1A1KDM4ELMNAHTTHSD17B10 | |
| SCHEMBL3182095 | 0.78 | ALDH1A1 (0.67) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL5388878 | 0.78 | MAOB (0.45) | ALDH1A1KDM4EHPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431762-A | HYDROXY-SUBSTITUTED NAPTHANILIDES; MOLDING MATERIALS; PROTECTIVE COATINGS; FILMS | DAINIPPON INK & CHEMICALS INC. (JP) | 1984-02-14 | — | — | US | claimed |