Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PLEC | Q15149 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11659997 | 0.89 | MAOA (0.54) | ALDH1A1KDM4EHTTLMNAHSD17B10 | |
| SCHEMBL11595676 | 0.89 | RAB9A (0.56) | ALDH1A1KDM4EHTTLMNAHSD17B10 | |
| SCHEMBL11561031 | 0.87 | MAPT (0.52) | ALDH1A1KDM4EHTTLMNAMAPK1 | |
| SCHEMBL11770628 | 0.87 | NPC1 (0.53) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL11662821 | 0.85 | NPC1 (0.52) | ALDH1A1KDM4EHPGDHTTMAOB | |
| SCHEMBL11776026 | 0.85 | MAPT (0.49) | KDM4EHPGDHTTLMNAAKR1C3 | |
| SCHEMBL11665696 | 0.84 | MAPT (0.55) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL11096556 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHTTLMNA | |
| SCHEMBL11660008 | 0.82 | KMT2A (0.60) | HTTLMNAMAPK1HSD17B10MAOB | |
| SCHEMBL11598294 | 0.82 | PPARG (0.45) | ALDH1A1KDM4EHPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4131733-A | PIGMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-12-26 | — | — | US | disclosed |
| US-4096157-A | PIGMENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-3939194-A | Bis-2-azomethine pigments, process for their manufacture and their use | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |