Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218136 | 0.83 | CYP1A2 (0.58) | HPGDMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3182095 | 0.82 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ELMNAMAPK1 | |
| SCHEMBL11096556 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDKDM4ELMNAMAPK1 | |
| SCHEMBL9706802 | 0.79 | DEGS1 (0.60) | ALDH1A1HPGDKDM4ELMNAHTT | |
| SCHEMBL8477167 | 0.79 | PLK1 (0.64) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL10889856 | 0.78 | MEN1 (0.78) | ALDH1A1HPGDKDM4ELMNAMAPK1 | |
| SCHEMBL29372498 | 0.78 | POLB (0.72) | ALDH1A1HPGDKDM4ELMNAMAPK1 | |
| SCHEMBL1344307 | 0.78 | POLB (0.72) | ALDH1A1HPGDKDM4ELMNAMAPK1 | |
| SCHEMBL30516994 | 0.78 | POLB (0.72) | ALDH1A1HPGDKDM4ELMNAMAPK1 | |
| SCHEMBL11624948 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055218-B1 | MANUFACTURE OF AZOIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1986-03-26 | — | — | EP | disclosed |
| US-4496481-A | REACTING AMINE, COUPLING COMPONENT AND NITRITE;PIGMENTS AND DISPERSE DYES | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0055218-A2 | Manufacture of azoic compounds | CIBA-GEIGY AG (CH) | 1982-06-30 | — | — | EP | disclosed |