SCHEMBL1109671

SCHEMBL1109671

O=C(O)C(=O)CC(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC5 P28715 10/20 1.00
FEN1 P39748 10/20 1.00
PTPN1 P18031 5/20 1.00
HAO1 Q9UJM8 5/20 0.77
MEN1 O00255 2/20 0.73
CYP3A4 P08684 2/20 0.73
HPGD P15428 2/20 0.73
KMT2A Q03164 2/20 0.73
KDM4E B2RXH2 1/20 0.73
MAPT P10636 1/20 0.73
ALOX15 P16050 1/20 0.73
CES1 P23141 1/20 0.73
MAPK1 P28482 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
PLOD2 O00469 1/20 0.57
PLOD3 O60568 1/20 0.57
ALDH1A1 P00352 1/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27655689 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL27835156 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL28005060 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL27573155 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL27742318 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL30364011 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL27691553 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL27316384 0.98 ERCC5 (0.95) ERCC5FEN1PTPN1HAO1MEN1
SCHEMBL9648913 0.90 ERCC5 (0.82) ERCC5FEN1PTPN1HAO1MEN1
Dibenzoylmethane SCHEMBL29586365 0.87 MEN1 (0.94) ERCC5FEN1PTPN1HAO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6599370-B2 Stabilized alkaline compositions for cleaning microelectronic substrates MALLINCKRODT INC. 2003-07-29 US claimed
US-6585825-B1 Metal ion free solution containing base, silicate, stabilizer and water; removing photoresist residues and other metallic and organic contaminates from semiconductor wafers without damaging MALLINCKRODT INC 2003-07-01 US claimed
WO-2000066588-A1 DIRECT C-14 OXIDATION OF OPIOIDS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENTOF HEALTH A ND HUMAN SERVICES (US) 2000-11-09 WO claimed
EP-0362012-B1 Stabiliser compositions for halogenated polymers containing beta-diketone, hydrotalcite and dihydropyridine, and polymers stabilized therewith ATOCHEM ELF SA (FR) 1993-12-29 EP claimed
EP-0518908-A1 METHOD FOR POLYMERIZATION OF EPOXIDE COMPOUNDS. RUETGERSWERKE AG (DE) 1992-12-23 EP claimed
WO-1991013925-A1 METHOD FOR POLYMERIZATION OF EPOXIDE COMPOUNDS RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1991-09-19 WO claimed
JP-5286890-A None JP disclosed
US-20250213569-A1 METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY NEW YORK UNIVERSITY (US) 2025-07-03 US disclosed
CN-117337276-B Process for recycling ethylene in an ethylene oligomerization reactor system 切弗朗菲利浦化学公司 2025-02-07 CN disclosed
CN-118974272-A Label fragmenting workflow 因美纳有限公司 2024-11-15 CN disclosed
EP-3022792-B1 LOW TEMPERATURE SOLID OXIDE CELLS FCET INC (US) 2024-09-11 EP disclosed
CN-118574804-A Heat exchange configuration for olefin oligomerization 切弗朗菲利浦化学公司 2024-08-30 CN disclosed
US-12071697-B2 Low temperature electrolytes for solid oxide cells having high ionic conductivity FCET, INC. (US) 2024-08-27 US disclosed
US-4369206-A HARDENING COATING WITH AMINES BAYER AKTIENGESELLSCHAFT (DE) 1983-01-18 US disclosed
US-4315932-A AND SULFANILAMIDES BURROUGHS WELLCOME CO. (US) 1982-02-16 US disclosed
US-4288365-A 1H-PYRIMIDO(4,5-C)-1,2-DIAZEPINES BURROUGHS WELLCOME CO. (US) 1981-09-08 US disclosed
EP-0004079-B1 SUPPORT CATALYST FOR THE PREPARATION OF VINYL ACETATE FROM ETHYLENE, ACETIC ACID AND OXYGEN IN THE GASEOUS PHASE. HOECHST AKTIENGESELLSCHAFT (DE) 1981-06-17 EP disclosed
US-4260758-A MICROBIOCIDES BURROUGHS WELLCOME CO. (US) 1981-04-07 US disclosed
US-4237289-A MICROBIOCIDES BURROUGHS WELLCOME CO. (US) 1980-12-02 US disclosed
EP-0004079-A2 Support catalyst for the preparation of vinyl acetate from ethylene, acetic acid and oxygen in the gaseous phase. HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213569-A1 METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY DCLRE1B, RNASE1, ADAR ERCC5 258/4885FEN1 10/4885PTPN1 1892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.