Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588929 | 0.85 | BCHE (0.34) | HPGDKMT2ALMNATSHRBCHE | |
| SCHEMBL5801660 | 0.84 | KEAP1 (0.42) | KMT2ALMNARXFP1 | |
| SCHEMBL5801752 | 0.75 | MAPT (0.36) | HPGDKMT2AALDH1A1POLB | |
| SCHEMBL20263764 | 0.71 | MAPT (0.36) | HPGDKMT2ATSHRBCHEACHE | |
| Hydrochloric Acid SCHEMBL28857820 | 0.70 | POLB (0.35) | TSHRBCHEACHEPOLB | |
| SCHEMBL8488065 | 0.63 | AKR1B1 (0.46) | AKR1B1ABCC4LMNAGAATSHR | |
| SCHEMBL16684853 | 0.63 | AKR1B1 (0.38) | AKR1B1HPGDKMT2AABCC4LMNA | |
| SCHEMBL8087155 | 0.63 | AKR1B1 (0.42) | AKR1B1ABCC4LMNAGAATSHR | |
| SCHEMBL27848247 | 0.62 | PTPN1 (0.50) | AKR1B1HPGDKMT2AABCC4LMNA | |
| SCHEMBL7827157 | 0.61 | AKR1B1 (0.67) | AKR1B1ABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125056-A2 | Condensed, seven-membered ring compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-11-14 | — | — | EP | disclosed |