Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588929 | 0.73 | BCHE (0.34) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL5801660 | 0.72 | KEAP1 (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL20263764 | 0.66 | MAPT (0.36) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL27459325 | 0.62 | TSHR (0.42) | MAPTHPGDALDH1A1POLB | |
| SCHEMBL10727947 | 0.62 | GPR84 (0.47) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL8086115 | 0.59 | MEN1 (0.34) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL11739195 | 0.59 | GPR84 (0.36) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL8831213 | 0.58 | KDM4E (0.34) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL4137654 | 0.57 | ALDH1A1 (0.47) | MAPTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL3650633 | 0.57 | TRPA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006079077-A2 | USE OF DILTIAZEM OR ANALOGS THEREOF AS MODULATORS OF GHRELIN RECEPTOR | ACADIA PHARMACEUTICALS INC. (US) | 2006-07-27 | — | — | WO | disclosed |