Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 12/20 | 0.48 |
| ▸ | CES1 | P23141 | 11/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865759 | 0.84 | CES2 (0.52) | MEN1KMT2ACES2CES1MAPT | |
| SCHEMBL23934158 | 0.78 | MEN1 (0.46) | MEN1KMT2ACES2CES1MAPT | |
| SCHEMBL9818400 | 0.78 | RAB9A (0.46) | MEN1KMT2ACES2CES1MAPT | |
| SCHEMBL11721438 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2ACES2CES1MAPT | |
| SCHEMBL10418288 | 0.70 | SMN1; SMN2 (0.46) | MEN1KMT2ACES2CES1MAPT | |
| SCHEMBL28736082 | 0.69 | CES2 (0.54) | MEN1KMT2ACES2CES1MAPT | |
| Benzil SCHEMBL27655380 | 0.69 | CES2 (0.88) | CES2CES1MAPTALDH1A1LMNA | |
| Benzil SCHEMBL4832229 | 0.69 | CES2 (0.88) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL24729196 | 0.69 | KDM1A (0.42) | MEN1KMT2ACES2CES1MAPT | |
| Benzil SCHEMBL66 | 0.68 | CES2 (1.00) | MEN1KMT2ACES2CES1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476313-A | PHOTOCOPYING | RENSSELAER POLYTECHNIC INSTITUTE (US) | 1984-10-09 | — | — | US | disclosed |