Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | RGS12 | O14924 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097037 | 1.00 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL11303376 | 0.87 | GABBR2 (0.58) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL11303373 | 0.87 | GABBR2 (0.58) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL11305941 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL9580152 | 0.81 | GABBR2 (0.55) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL9684949 | 0.81 | GABBR2 (0.55) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL7175613 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL30421233 | 0.78 | HMGCR (0.47) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL6937644 | 0.78 | GABBR2 (0.60) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT | |
| SCHEMBL7824832 | 0.78 | GABBR2 (0.60) | ALDH1A1SMN1; SMN2MEN1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440784-A | 3,5-DI-TERT-BUTYL-4-HYDROXYSTYRENE DERIVATIVE | KANEGAFUCHI CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0057881-A2 | An anti-inflammatory, analgesic, and antipyretic pharmaceutical composition, and method for producing it | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-08-18 | — | — | EP | disclosed |