Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.55 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RGS12 | O14924 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580152 | 1.00 | GABBR2 (0.55) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL11305941 | 0.91 | ALDH1A1 (0.54) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL7824832 | 0.91 | GABBR2 (0.60) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL11303376 | 0.83 | GABBR2 (0.58) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL11303373 | 0.83 | GABBR2 (0.58) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL6937644 | 0.81 | GABBR2 (0.60) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL11097037 | 0.81 | ALDH1A1 (0.54) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL11097041 | 0.81 | ALDH1A1 (0.54) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL9185664 | 0.80 | GABBR2 (0.49) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL9185650 | 0.80 | GABBR2 (0.49) | GABBR2GABBR1ALDH1A1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500426-A1 | 2,6-Dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine derivatives, process for their preparation and their use as free radical scavengers | Instituto de Investigacion Y Desarrollo Quimico-Biologico S.A. (ES) | 1992-08-26 | — | — | EP | disclosed |