Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11091882 | 0.89 | BRD4 (0.36) | OPRM1BRD4MAPTGAACYP2C19 | |
| SCHEMBL11097162 | 0.85 | BRD4 (0.40) | OPRM1BRD4MAPTGAACYP2C19 | |
| SCHEMBL11095941 | 0.85 | OPRM1 (0.39) | OPRM1BRD4GAAALDH1A1KDM4E | |
| SCHEMBL11090700 | 0.84 | ADORA3 (0.38) | OPRM1BRD4MAPTGAACYP2C19 | |
| SCHEMBL11099865 | 0.82 | BRD4 (0.43) | OPRM1BRD4MAOBL3MBTL1OPRD1 | |
| SCHEMBL11092748 | 0.82 | GAA (0.35) | MAPTGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL11093637 | 0.80 | BRD4 (0.38) | OPRM1BRD4MAPTGAACYP2C19 | |
| SCHEMBL11093534 | 0.79 | CYP11B2 (0.40) | OPRM1MAPTGAACYP2C19ALDH1A1 | |
| SCHEMBL11095394 | 0.78 | RAB9A (0.38) | MAPTGAAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11098282 | 0.78 | BRD4 (0.37) | OPRM1BRD4MAPTGAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4436666-A | HERBICIDES, MITICIDWS | UNION CARBIDE CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |