Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.46 |
| ▸ | TUBB | P07437 | 6/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258031 | 0.91 | LMNA (0.69) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11809362 | 0.89 | LMNA (0.51) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11667061 | 0.86 | LMNA (0.48) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14097446 | 0.84 | TUBB4A (0.50) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| Albendazole SCHEMBL28325579 | 0.82 | LMNA (0.72) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11096138 | 0.81 | TUBB4A (0.48) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7258034 | 0.81 | LMNA (0.83) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| Albendazole SCHEMBL29409236 | 0.81 | LMNA (0.83) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| Albendazole SCHEMBL44682 | 0.81 | LMNA (0.83) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| Albendazole SCHEMBL7969988 | 0.81 | LMNA (0.83) | LMNACYP1A2SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487936-A | Preparation of alkylthiobenzimidazoles | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1984-12-11 | — | — | US | disclosed |
| EP-0031473-B1 | PROCESS FOR PREPARING 2-((ALKOXYCARBONYL)-AMINO)-5-(ALKYLTHIO)-1H-BENZIMIDAZOLES | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1984-05-30 | — | — | EP | disclosed |
| US-4368328-A | ANTHELMINTICS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-01-11 | — | — | US | disclosed |