Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.47 |
| ▸ | TUBB | P07437 | 6/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809370 | 0.90 | LMNA (0.63) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11097207 | 0.89 | LMNA (0.56) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20909217 | 0.87 | LMNA (0.60) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11667061 | 0.87 | LMNA (0.48) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7258031 | 0.87 | LMNA (0.69) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14097446 | 0.85 | TUBB4A (0.50) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11096138 | 0.82 | TUBB4A (0.48) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11104041 | 0.81 | LMNA (0.56) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31265130 | 0.81 | LMNA (0.53) | LMNACYP1A2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5382918 | 0.80 | KDR (0.72) | CYP1A2SMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956499-A | ANTHELMINTICS | SMITHKLINE CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |