Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820396 | 0.74 | HPGD (0.36) | ALOX5KDM4ELMNANPC1RAB9A | |
| SCHEMBL547888 | 0.74 | ALOX5 (0.40) | ALOX5KDM4ELMNANPC1RAB9A | |
| SCHEMBL802241 | 0.73 | KDM4E (0.38) | ALOX5KDM4ELMNANPC1RAB9A | |
| SCHEMBL19718161 | 0.67 | SMN1; SMN2 (0.38) | ALOX5KDM4ELMNANPC1GAA | |
| SCHEMBL29085531 | 0.65 | KDM4E (0.36) | ALOX5KDM4ELMNAHPGD | |
| SCHEMBL2959546 | 0.61 | ALOX5 (0.43) | ALOX5KDM4ELMNANPC1GAA | |
| SCHEMBL8985724 | 0.61 | — | — | |
| SCHEMBL27008259 | 0.60 | LMNA (0.48) | ALOX5KDM4ELMNANPC1GAA | |
| SCHEMBL2968806 | 0.60 | ALOX5 (0.39) | ALOX5KDM4ELMNANPC1GAA | |
| SCHEMBL31424940 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481224-A | POSSIBLE REPLACEMENT FOR MONOSODIUM GLUTAMATE IN FOODS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-11-06 | — | — | US | disclosed |