Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.49 |
| ▸ | ATP4B | P51164 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 5/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 5/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 5/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 5/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189993 | 0.88 | ATP4A (0.60) | ATP4AATP4BHRH3BRD4MAPK1 | |
| Dimebutic Acid SCHEMBL10535100 | 0.83 | ATP4A (0.47) | ATP4AATP4BHRH3BRD4MAPK1 | |
| SCHEMBL2191140 | 0.78 | MEN1 (0.51) | ATP4AATP4BHRH3MAPK1CYP2C9 | |
| SCHEMBL2194287 | 0.77 | PPARG (0.50) | ATP4AATP4BHRH3MAPK1CYP2C9 | |
| SCHEMBL11096196 | 0.77 | ATP4A (0.50) | ATP4AATP4BHRH3BRD4MAPK1 | |
| SCHEMBL11070583 | 0.76 | KDM4E (0.52) | ATP4AATP4BHRH3MAPK1CYP2C9 | |
| SCHEMBL7849956 | 0.76 | PPARG (0.60) | ATP4AATP4BHRH3MAPK1CYP2C9 | |
| SCHEMBL10675888 | 0.75 | NPC1 (0.51) | ATP4AATP4BMEN1KMT2AMAPT | |
| SCHEMBL11100065 | 0.74 | ATP4A (0.47) | ATP4AATP4BHRH3MAPK1CYP2C9 | |
| SCHEMBL9746834 | 0.74 | PPARG (0.50) | ATP4AATP4BMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033094-B1 | IMIDAZO(1,2-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-10-10 | — | — | EP | claimed |