Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.50 |
| ▸ | ATP4B | P51164 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498513 | 0.90 | PTGER1 (0.47) | PTGER1RXRARXRB | |
| SCHEMBL11070583 | 0.86 | KDM4E (0.52) | ATP4AATP4BHRH3MEN1CYP1A2 | |
| SCHEMBL7274305 | 0.84 | PSEN1 (0.48) | ATP4AATP4BPTGS1PTGS2PTGER1 | |
| SCHEMBL2191622 | 0.80 | ATP4A (0.55) | ATP4AATP4BHRH3BRD4MEN1 | |
| SCHEMBL2189993 | 0.80 | ATP4A (0.60) | ATP4AATP4BHRH3BRD4MEN1 | |
| SCHEMBL1201345 | 0.79 | PTGS1 (0.50) | PTGS1PTGS2P4HTMKMT2A | |
| SCHEMBL11067780 | 0.78 | ATP4A (0.52) | ATP4AATP4BHRH3BRD4MEN1 | |
| SCHEMBL11097237 | 0.77 | ATP4A (0.49) | ATP4AATP4BHRH3PTGER1BRD4 | |
| SCHEMBL2193708 | 0.77 | ATP4A (0.54) | ATP4AATP4BHRH3BRD4MEN1 | |
| SCHEMBL11094768 | 0.77 | KDM4E (0.50) | ATP4AATP4BMEN1KMT2APSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033094-B1 | IMIDAZO(1,2-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-10-10 | — | — | EP | disclosed |
| EP-0033094-A1 | Imidazo(1,2-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |