SCHEMBL1276853

SCHEMBL1276853

C[SiH](C)N(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
MEN1 O00255 2/20 0.40
HTT P42858 1/20 0.40
FAAH O00519 1/20 0.39
PHGDH O43175 1/20 0.39
MGLL Q99685 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 4/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALOX15 P16050 1/20 0.36
KDM4E B2RXH2 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10879003 0.82 NPSR1 (0.42) KMT2AMEN1HTTFAAHPHGDH
SCHEMBL1276854 0.77 KMT2A (0.40) KMT2AMEN1HTTFAAHPHGDH
SCHEMBL9621566 0.76 MEN1 (0.36) KMT2AMEN1HTTFAAHPHGDH
SCHEMBL10652728 0.75 ALDH1A1 (0.39) KMT2AMEN1HTTFAAHPHGDH
SCHEMBL9621445 0.74 ALDH1A1 (0.39) KMT2AMEN1HTTCA12CA2
SCHEMBL12506407 0.72 ALDH1A1 (0.33) KMT2AMEN1HTTALDH1A1NPSR1
SCHEMBL7037971 0.72 ALDH1A1 (0.37) KMT2AMEN1HTTFAAHPHGDH
SCHEMBL10393863 0.71 ALDH1A1 (0.56) KMT2AMEN1HTTL3MBTL1LMNA
SCHEMBL10654718 0.70 TSHR (0.40) KMT2AMEN1HTTL3MBTL1LMNA
SCHEMBL3152408 0.69 LMNA (0.42) KMT2AMEN1HTTFAAHPHGDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109906235-B Process for producing modified diene-containing rubbers, rubbers and compositions based thereon 公共型股份公司希布尔控股 2021-11-12 CN claimed
CN-109906235-A Produce method, rubber and the composition based on it of the modified rubber containing diene 公共型股份公司希布尔控股 2019-06-18 CN claimed
CN-109906235-B Process for producing modified diene-containing rubbers, rubbers and compositions based thereon 公共型股份公司希布尔控股 2021-11-12 CN disclosed
CN-109689826-B Fast curing optical adhesives 3M创新有限公司 2021-10-29 CN disclosed
US-10436984-B2 Optical fiber splice element and optical network 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-10-08 US disclosed
US-10329460-B2 Fast curing optical adhesive 3M INNOVATIVE PROPERTIES COMPANY (US) 2019-06-25 US disclosed
CN-109906235-A Produce method, rubber and the composition based on it of the modified rubber containing diene 公共型股份公司希布尔控股 2019-06-18 CN disclosed
EP-3467300-A1 NOZZLE 3M Innovative Properties Co. (US) 2019-04-10 EP disclosed
US-20180363613-A1 NOZZLE AND METHOD OF MAKING SAME 3M INNOVATIVE PROPERTIES CO (US) 2018-12-20 US disclosed
US-10054094-B2 Microstructured pattern for forming a nozzle pre-form 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-08-21 US disclosed
WO-2018052777-A1 FAST CURING OPTICAL ADHESIVE 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-22 WO disclosed
EP-0184692-A1 Method of preparation of o-silylated ketene acetals and enol ethers UNION CARBIDE CORPORATION (US) 1986-06-18 EP disclosed
EP-0098912-B1 PROCESS FOR THE PREPARATION OF ALKOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-23 EP disclosed
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
EP-0112434-A2 Hydrogen bearing silyl carbamates UNION CARBIDE CORPORATION (US) 1984-07-04 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4400526-A Hydrogen bearing silyl carbamates UNION CARBIDE CORPORATION (US) 1983-08-23 US disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed