Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097240 | 0.77 | TSHR (0.43) | TSHRALDH1A1CYP2C19CNR2GLA | |
| SCHEMBL10654410 | 0.75 | TSHR (0.54) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL10647482 | 0.74 | TP53 (0.40) | TSHRALDH1A1GLASLC6A2SLC6A4 | |
| SCHEMBL3138984 | 0.73 | TSHR (0.58) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL27259195 | 0.71 | TSHR (0.56) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL8760943 | 0.71 | ESR1 (0.38) | TSHRALDH1A1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9621506 | 0.70 | TSHR (0.54) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL642317 | 0.70 | CRHBP (0.61) | TSHRALDH1A1AOC3CARM1PRMT6 | |
| SCHEMBL43183 | 0.69 | TSHR (0.74) | TSHRALDH1A1AOC3CYP2C19CNR2 | |
| SCHEMBL918512 | 0.69 | NR3C2 (0.56) | TSHRALDH1A1AOC3CYP2C19CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112434-A2 | Hydrogen bearing silyl carbamates | UNION CARBIDE CORPORATION (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4400526-A | Hydrogen bearing silyl carbamates | UNION CARBIDE CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |