SCHEMBL1109744

SCHEMBL1109744

C1=C(/c2ccccc2)CCCCCC/1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 2/20 0.47
ELANE P08246 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTGS2 P35354 1/20 0.45
SIGMAR1 Q99720 1/20 0.43
HTR2C P28335 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
FFAR2 O15552 1/20 0.41
MAT2A P31153 1/20 0.40
SERPINE1 P05121 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1109740 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL1094677 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL1094678 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL8356129 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL8359816 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL1094676 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL1109745 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL8360447 1.00 ACMSD (0.47) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL191429 0.98 ACMSD (0.49) ACMSDELANETDP1PTGS2SIGMAR1
SCHEMBL8380044 0.98 ACMSD (0.49) ACMSDELANETDP1PTGS2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737513-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737517-A1 RUBBER COMPOSITION FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737515-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
EP-4737516-A1 RUBBER COMPOSITION FOR TIRES, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-05-06 EP disclosed
US-20250263511-A1 COPOLYMER FORMED BY RING-OPENING COPOLYMERIZATION OF CYCLOOLEFIN, PRODUCTION METHOD THEREFOR, RUBBER COMPOSITION, AND CROSSLINKED RUBBER OBJECT ZEON CORPORATION (JP) 2025-08-21 US disclosed
WO-2025100025-A1 TREAD RUBBER COMPOSITION, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-05-15 WO disclosed
WO-2025070000-A1 RUBBER COMPOSITION, CROSSLINKED RUBBER, AND TIRE 日本ゼオン株式会社 2025-04-03 WO disclosed
US-20250091969-A1 CYCLOPENTENE RECOVERY METHOD ZEON CORPORATION (JP) 2025-03-20 US disclosed
EP-3822317-B1 RING-OPENING COPOLYMER COMPOSITION ZEON CORP (JP) 2025-02-26 EP disclosed
EP-4502058-A1 RUBBER COMPOSITION AND CROSSLINKED RUBBER OBJECT Zeon Corporation (JP) 2025-02-05 EP disclosed
WO-2008033894-A2 COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS ACADIA PHARMACEUTICALS INC. (US) 2008-03-20 WO disclosed
EP-1862484-A1 NORBORNENE ADDITION COPOLYMER AND MOLDINGS ZEON CORPORATION (JP) 2007-12-05 EP disclosed
WO-2007056500-A2 COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTORS ACADIA PHARMACEUTICALS INC. (US) 2007-05-18 WO disclosed
EP-1747182-A2 COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTOR Acadia Pharmaceuticals Inc. (US) 2007-01-31 EP disclosed
US-20060122278-A1 di-aromatic compounds for treatment and prevention of diseases and disorders related to estrogen receptors; 2-fluoro-1-methoxy-4-(1-phenyl-cyclohexyl)-benzene ACADIA PHARMACEUTICALS INC. 2006-06-08 US disclosed
US-20050256210-A1 Compounds with activity at estrogen receptors ACADIA PHARMACEUTICALS INC. 2005-11-17 US disclosed
WO-2005108337-A2 COMPOUNDS WITH ACTIVITY AT ESTROGEN RECEPTOR ACADIA PHARMACEUTICALS INC. (US) 2005-11-17 WO disclosed
US-20050065060-A1 Solvents containing cycloakyl alkyl ethers and process for production of the ethers ZEON CORPORATION (JP) 2005-03-24 US disclosed
EP-1405840-A1 SOLVENTS CONTAINING CYCLOALKYL ALKYL ETHERS AND PROCESS FOR PRODUCTION OF THE ETHERS Zeon Corporation (JP) 2004-04-07 EP disclosed
WO-1998049128-A1 PROCESS FOR PREPARING A (HETERO)AROMATIC OLEFIN DSM N.V. (NL) 1998-11-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091969-A1 CYCLOPENTENE RECOVERY METHOD CYC1, CYCS, DHPS ACMSD 807/4885ELANE 927/4885TDP1 809/4885
US-20060122278-A1 di-aromatic compounds for treatment and prevention of diseases and disorders related to estrogen receptors; 2-fluoro-1-methoxy-4-(1-phenyl-cyclohexyl)-benzene GPER1, ESR1, ESR2 ACMSD 1826/4885ELANE 1816/4885TDP1 1590/4885
US-20050256210-A1 Compounds with activity at estrogen receptors ESR2, GPER1, ESRRG ACMSD 4369/4885ELANE 982/4885TDP1 2334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.