Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102767 | 0.92 | NR3C1 (0.62) | NR3C1TSHRALDH1A1KDM4ERAB9A | |
| SCHEMBL13414998 | 0.82 | ABCB1 (0.44) | NR3C1ALDH1A1KDM4EGAAPOLB | |
| SCHEMBL27838089 | 0.79 | NR3C1 (0.56) | NR3C1TSHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11097182 | 0.78 | LMNA (0.50) | ALDH1A1KDM4EGAARAB9ACYP3A4 | |
| SCHEMBL178911 | 0.78 | NR3C1 (0.59) | NR3C1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL178909 | 0.77 | NR3C1 (0.58) | NR3C1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL13359889 | 0.77 | NR3C1 (0.58) | NR3C1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL8225508 | 0.77 | NR3C1 (0.58) | NR3C1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL178924 | 0.75 | NR3C1 (0.53) | NR3C1TSHRALDH1A1KDM4EGAA | |
| SCHEMBL6234654 | 0.75 | ALDH1A1 (0.48) | NR3C1ALDH1A1KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046307-B1 | NOVEL URACIL DERIVATIVES, PROCESS FOR PREPARING THE SAME AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-11-21 | — | — | EP | disclosed |
| US-4415573-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS; REACTING A 1,3-DIOXOLANE AND A URACIL USING AN ACID CATALYST AND SOLVENT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0046307-A1 | Novel uracil derivatives, process for preparing the same and a pharmaceutical composition containing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1982-02-24 | — | — | EP | disclosed |