Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15962938 | 0.85 | GPR139 (0.59) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6381157 | 0.84 | GPR139 (0.58) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL11108039 | 0.83 | GPR139 (0.52) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL17369074 | 0.82 | GPR139 (0.60) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8596105 | 0.75 | GPR139 (0.56) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL11097673 | 0.75 | GPR139 (0.63) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2673046 | 0.74 | CYP26A1 (0.48) | GPR139KMT2AALDH1A1TP53MEN1 | |
| SCHEMBL8725848 | 0.74 | GPR139 (0.56) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL9352752 | 0.74 | GPR139 (0.56) | GPR139KMT2AMAPTALDH1A1HTT | |
| SCHEMBL11108513 | 0.73 | PPID (0.50) | KMT2AALDH1A1TP53MEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444690-A | RADIOPHARMACEUTICALS FOR MAMMALIAN RENAL SYSTEMS | UNIVERSITY PATENTS, INC. (US) | 1984-04-24 | — | — | US | disclosed |