Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596105 | 0.82 | GPR139 (0.56) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8123498 | 0.79 | GPR139 (0.71) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8123489 | 0.79 | GPR139 (0.71) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL8596109 | 0.77 | GPR139 (0.56) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL6889605 | 0.76 | KMT2A (0.54) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL12642206 | 0.76 | GPR139 (0.62) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11098136 | 0.75 | GPR139 (0.54) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL17369074 | 0.74 | GPR139 (0.60) | GPR139KMT2AALDH1A1MAPTHTT | |
| SCHEMBL9082829 | 0.74 | ESRRB (0.49) | GPR139KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL10639568 | 0.74 | ESRRB (0.49) | GPR139KMT2AALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444690-A | RADIOPHARMACEUTICALS FOR MAMMALIAN RENAL SYSTEMS | UNIVERSITY PATENTS, INC. (US) | 1984-04-24 | — | — | US | disclosed |