Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657584 | 0.93 | RAB9A (0.57) | GAARAB9ANPC1HCRTR1RPS6KA3 | |
| SCHEMBL11100265 | 0.92 | HCRTR1 (0.61) | GAARAB9ANPC1HCRTR1PTGS1 | |
| SCHEMBL11096424 | 0.86 | RAB9A (0.61) | GAARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL11099353 | 0.84 | NPC1 (0.50) | GAARAB9ANPC1PPIA | |
| SCHEMBL8663087 | 0.82 | RAB9A (0.51) | GAARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL11100900 | 0.81 | RAB9A (0.55) | GAARAB9ANPC1HCRTR1RPS6KA3 | |
| SCHEMBL8659238 | 0.79 | RAB9A (0.65) | RAB9ANPC1ALDH1A1MAPTSCN9A | |
| SCHEMBL11264322 | 0.79 | GAA (0.52) | GAATLR7RAB9ANPC1KDM4E | |
| SCHEMBL11181555 | 0.78 | SMN1; SMN2 (0.58) | GAATLR7NPC1KDM4EALDH1A1 | |
| SCHEMBL11339685 | 0.77 | TLR7 (0.57) | GAATLR7RAB9AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281003-A | 1-(2-6-Dihalobenzoyl)-3-(5-substituted-2-pyridinyl)urea insecticides and insecticidal method | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| EP-0033231-B1 | INSECTICIDAL COMPOSITIONS CONTAINING 2,6-DIHALOBENZOYLUREA DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |
| US-4338321-A | FOR INCLUSION IN CATTLE OR POULTRY FEEDS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0033231-A1 | Insecticidal compositions containing 2,6-dihalobenzoylurea derivatives | ELI LILLY AND COMPANY (US) | 1981-08-05 | — | — | EP | disclosed |
| US-4281003-A | 1-(2-6-Dihalobenzoyl)-3-(5-substituted-2-pyridinyl)urea insecticides and insecticidal method | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |