Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.51 |
| ▸ | IL2 | P60568 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261749 | 0.94 | RAB9A (0.46) | GAAL3MBTL1TLR7MAPTRAB9A | |
| SCHEMBL11254846 | 0.93 | EPHX2 (0.46) | GAAL3MBTL1IL2MAPTRAB9A | |
| SCHEMBL11300373 | 0.85 | RAB9A (0.56) | L3MBTL1TLR7IL2MAPTRAB9A | |
| SCHEMBL11271217 | 0.85 | LMNA (0.46) | GAAL3MBTL1MAPTRAB9AKDM4E | |
| SCHEMBL11268396 | 0.85 | GAA (0.50) | GAAMAPTRAB9ANPSR1NPC1 | |
| SCHEMBL11296385 | 0.84 | IL2 (0.51) | L3MBTL1TLR7IL2MAPTRAB9A | |
| SCHEMBL11269508 | 0.81 | TRPV1 (0.48) | GAAL3MBTL1TLR7IL2TLR8 | |
| SCHEMBL11266098 | 0.81 | GAA (0.52) | GAAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL11258942 | 0.81 | RAB9A (0.50) | L3MBTL1MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL11261217 | 0.80 | TLR7 (0.46) | GAAL3MBTL1TLR7IL2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | claimed |