Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656115 | 0.91 | RAB9A (0.56) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL11104934 | 0.91 | NPC1 (0.55) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL11096424 | 0.88 | RAB9A (0.61) | NPC1RAB9AMEN1KMT2APPIA | |
| SCHEMBL11098486 | 0.84 | GAA (0.55) | NPC1RAB9APPIAGAA | |
| SCHEMBL8663087 | 0.84 | RAB9A (0.51) | NPC1RAB9AMEN1KMT2APPIA | |
| SCHEMBL11189594 | 0.82 | RAB9A (0.47) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL8659238 | 0.81 | RAB9A (0.65) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL2728441 | 0.81 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL11163699 | 0.78 | RAB9A (0.68) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11036041 | 0.77 | SMN1; SMN2 (0.54) | NPC1RAB9AMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281003-A | 1-(2-6-Dihalobenzoyl)-3-(5-substituted-2-pyridinyl)urea insecticides and insecticidal method | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| EP-0033231-B1 | INSECTICIDAL COMPOSITIONS CONTAINING 2,6-DIHALOBENZOYLUREA DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |
| US-4338321-A | FOR INCLUSION IN CATTLE OR POULTRY FEEDS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0033231-A1 | Insecticidal compositions containing 2,6-dihalobenzoylurea derivatives | ELI LILLY AND COMPANY (US) | 1981-08-05 | — | — | EP | disclosed |
| US-4281003-A | 1-(2-6-Dihalobenzoyl)-3-(5-substituted-2-pyridinyl)urea insecticides and insecticidal method | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |