Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764465 | 0.82 | NPBWR1 (0.47) | HIF1AMAPK14ALDH1A1LMNAKDM4E | |
| SCHEMBL134480 | 0.78 | RAB9A (0.70) | MAPK14ALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3251762 | 0.77 | MAPK14 (0.57) | HIF1AMAPK14ALDH1A1LMNAKDM4E | |
| SCHEMBL17619922 | 0.77 | MAPK14 (0.50) | HIF1AMAPK14ALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL5402695 | 0.76 | MAPK14 (0.56) | HIF1AMAPK14ALDH1A1LMNAKDM4E | |
| SCHEMBL10769084 | 0.75 | RAB9A (0.71) | HIF1AALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL1815226 | 0.74 | MAPK14 (0.55) | HIF1AMAPK14ALDH1A1LMNAKDM4E | |
| SCHEMBL10672542 | 0.74 | RAB9A (0.58) | ALDH1A1LMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL3039419 | 0.72 | RAB9A (0.61) | HIF1AALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL22552613 | 0.72 | NPC1 (0.58) | HIF1AMAPK14ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027965-B1 | SUBSTITUTED UREAS, THEIR PREPARATION AND USE AS HERBICIDES, AND COMPOSITIONS THEREFOR | BASF Aktiengesellschaft (DE) | 1984-06-13 | — | — | EP | disclosed |