Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31097151 | 0.77 | HPGD (0.43) | HSD11B1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15551380 | 0.75 | LIPE (0.44) | HSD11B1KMT2AALDH1A1JAK1 | |
| SCHEMBL28019652 | 0.75 | LIPE (0.44) | HSD11B1KMT2AALDH1A1JAK1 | |
| SCHEMBL24518383 | 0.75 | LIPE (0.44) | HSD11B1KMT2AALDH1A1JAK1 | |
| SCHEMBL13613403 | 0.75 | ALDH1A1 (0.37) | ALDH1A1ALOX15DPP4 | |
| SCHEMBL11183229 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15HRH3 | |
| SCHEMBL11191482 | 0.71 | ALDH1A1 (0.37) | ALDH1A1ALOX15 | |
| SCHEMBL5072323 | 0.70 | CYP2C9 (0.38) | ALDH1A1ALOX15 | |
| SCHEMBL10156042 | 0.70 | ALDH1A1 (0.36) | ALDH1A1ALOX15 | |
| SCHEMBL8850098 | 0.70 | ALDH1A1 (0.36) | ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022079-B1 | POLYALKYLPIPERIDYL UREAS, THEIR APPLICATION AS STABILIZERS AND POLYMERS THUS STABILIZED | CIBA-GEIGY AG (CH) | 1984-01-18 | — | — | EP | disclosed |
| US-4412021-A | PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| EP-0022079-A1 | Polyalkylpiperidyl ureas, their application as stabilizers and polymers thus stabilized | CIBA-GEIGY AG (CH) | 1981-01-07 | — | — | EP | disclosed |