Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937237 | 0.83 | ALDH1A1 (0.32) | ALDH1A1ALOX15 | |
| SCHEMBL11183229 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ALOX15TSHRNFKB1CYP2C19 | |
| SCHEMBL5072323 | 0.77 | CYP2C9 (0.38) | ALDH1A1ALOX15NFKB1 | |
| SCHEMBL11191482 | 0.75 | ALDH1A1 (0.37) | ALDH1A1ALOX15TSHRNFKB1CYP2C19 | |
| SCHEMBL11098534 | 0.75 | HSD11B1 (0.38) | ALDH1A1ALOX15DPP4 | |
| SCHEMBL10156042 | 0.74 | ALDH1A1 (0.36) | ALDH1A1ALOX15 | |
| SCHEMBL8850098 | 0.74 | ALDH1A1 (0.36) | ALDH1A1ALOX15 | |
| SCHEMBL12206755 | 0.73 | CCR5 (0.36) | DPP4DPP9CCR5 | |
| SCHEMBL16219008 | 0.72 | DPP4 (0.47) | ALDH1A1DPP4DPP9CCR5 | |
| SCHEMBL24315821 | 0.70 | DPP4 (0.35) | DPP4DPP9CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312464-A1 | Stabilizer mixtures | GUGUMUS FRANCOIS | 2009-12-17 | — | — | US | disclosed |
| US-7332105-B2 | Synergistic UV absorber combination | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-02-19 | — | — | US | disclosed |
| US-7169835-B2 | Stabilizer mixture | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-01-30 | — | — | US | disclosed |