Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096295 | 0.88 | MAOB (0.51) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL11101577 | 0.83 | TSHR (0.53) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL11103886 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL1141274 | 0.82 | GAA (0.56) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL11097921 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| Potassium SCHEMBL7063916 | 0.80 | GAA (0.55) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| Lithium SCHEMBL7065338 | 0.80 | GAA (0.55) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL1726035 | 0.80 | GAA (0.55) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL11104797 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 | |
| SCHEMBL10487739 | 0.79 | CDC7 (0.58) | ALDH1A1MAPTGAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032748-B1 | THIOPHENE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |
| US-4421761-A | FUNGICIDES | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0032748-A1 | Thiophene derivatives | UBE INDUSTRIES, LTD. (JP) | 1981-07-29 | — | — | EP | disclosed |