Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103886 | 0.86 | ALDH1A1 (0.56) | TSHRALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL11098717 | 0.83 | ALDH1A1 (0.51) | TSHRALDH1A1LMNAHTTMEN1 | |
| SCHEMBL1086028 | 0.80 | KMT2A (0.56) | TSHRALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL1720659 | 0.78 | KMT2A (0.54) | TSHRALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL9826124 | 0.77 | TRPM8 (0.55) | TSHRALDH1A1LMNAL3MBTL1HTT | |
| SCHEMBL1086031 | 0.76 | MAPT (0.48) | TSHRALDH1A1LMNAL3MBTL1MEN1 | |
| Benzophenone SCHEMBL27524744 | 0.74 | TSHR (0.86) | TSHRALDH1A1LMNAL3MBTL1MEN1 | |
| SCHEMBL695012 | 0.72 | TSHR (0.83) | TSHRALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL68469 | 0.72 | PLA2G1B (0.60) | TSHRALDH1A1LMNAHTTMEN1 | |
| Methyl Benzoate SCHEMBL1867855 | 0.71 | TSHR (1.00) | TSHRALDH1A1LMNAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57116065-A | — | — | None | — | — | JP | disclosed |
| EP-0032748-B1 | THIOPHENE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |
| US-4421761-A | FUNGICIDES | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| JP-S57116065-A | THIOPHENE DERIVATIVE AND AGRICULTURAL AND GARDENING FUNGICIDE | HOKKO CHEM IND CO LTD | 1982-07-19 | — | — | JP | disclosed |
| EP-0032748-A1 | Thiophene derivatives | UBE INDUSTRIES, LTD. (JP) | 1981-07-29 | — | — | EP | disclosed |