Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13260805 | 0.87 | ALDH1A1 (0.47) | ALDH1A1TSHRHTTCES1KMT2A | |
| SCHEMBL11091632 | 0.85 | CES1 (0.53) | ALDH1A1TSHRHTTCES1MAPT | |
| SCHEMBL9749783 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TSHRHTTCES1MAPT | |
| SCHEMBL7911425 | 0.83 | CES1 (0.49) | ALDH1A1CES1MAPTKMT2AMEN1 | |
| SCHEMBL5574740 | 0.83 | CES1 (0.49) | ALDH1A1CES1MAPTKMT2AMEN1 | |
| SCHEMBL28235298 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRHTTMAPTKMT2A | |
| SCHEMBL914317 | 0.80 | CES1 (0.43) | ALDH1A1TSHRHTTCES1MAPT | |
| SCHEMBL14932471 | 0.78 | CES1 (0.44) | ALDH1A1CES1MAPTSMN1; SMN2CES2 | |
| SCHEMBL9718680 | 0.78 | CES1 (0.44) | ALDH1A1TSHRHTTCES1MAPT | |
| SCHEMBL6201588 | 0.77 | CES1 (0.43) | ALDH1A1TSHRCES1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129443-A2 | Curable compositions containing photoinitiators | LOCTITE CORPORATION (US) | 1984-12-27 | — | — | EP | disclosed |
| US-4477326-A | ULTRAVIOLET - CURABLE MIXTURE OF AN A-ALLYLBENZOIN ETHER-MODIFIED POLYSILOXANE AND UNSATURATED MONOMER; COATINGS | LOCTITE CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4391963-A | Organopolysiloxane photosensitizers and methods for their preparation | TORAY SILICONE COMPANY, LTD. (JP) | 1983-07-05 | — | — | US | disclosed |