Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 9/20 | 0.49 |
| ▸ | CES2 | O00748 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255415 | 0.90 | LMNA (0.50) | CES1CES2ALDH1A1MAPTSRC | |
| SCHEMBL7911425 | 0.90 | CES1 (0.49) | CES1CES2ALDH1A1MAPTSRC | |
| SCHEMBL36097 | 0.85 | CES1 (0.59) | CES1CES2SRCLMNAKMT2A | |
| SCHEMBL14932471 | 0.84 | CES1 (0.44) | CES1CES2ALDH1A1MAPTSRC | |
| SCHEMBL7945147 | 0.84 | CES1 (0.49) | CES1CES2ALDH1A1MAPTSRC | |
| SCHEMBL8020102 | 0.83 | CYP3A4 (0.41) | CES1CES2ALDH1A1MAPTLMNA | |
| SCHEMBL11098719 | 0.83 | ALDH1A1 (0.46) | CES1CES2ALDH1A1MAPTSRC | |
| SCHEMBL6201588 | 0.83 | CES1 (0.43) | CES1CES2ALDH1A1MAPTSRC | |
| SCHEMBL4810203 | 0.83 | CES1 (0.45) | CES1CES2ALDH1A1MAPTSRC | |
| SCHEMBL14932474 | 0.82 | CES1 (0.42) | CES1CES2ALDH1A1MAPTSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4266005-A | Photosensitive elastomeric composition | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-05-05 | — | — | US | claimed |
| EP-1786552-A1 | METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY | Applera Corporation (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20060078983-A1 | Polymer monolith substrate | APPLERA CORPORATION (US) | 2006-04-13 | — | — | US | disclosed |
| WO-2006026378-A1 | METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY | APPLERA CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |
| US-4868091-A | USING A BISACYLPHOSPHINE OXIDE PHOTOINITIATOR, UNSATURATED COMPOUND AND POLYMERIC BINDER; SHORT EXPOSURE TIME; NEWSPAPER PRINTING | BASF AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |
| US-4385109-A | ACYL PHOSPHINE OXIDE PHOTOINITIATOR | BASF AKTIENGESELLSCHAFT (DE) | 1983-05-24 | — | — | US | disclosed |
| US-4292152-A | UNSATURATED MONOMER, BINDER | BASF AKTIENGESELLSCHAFT (DE) | 1981-09-29 | — | — | US | disclosed |