Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914317 | 0.90 | CES1 (0.43) | CES1ALDH1A1TSHRHTTCYP3A4 | |
| SCHEMBL13260805 | 0.88 | ALDH1A1 (0.47) | CES1ALDH1A1TSHRHTTCYP3A4 | |
| SCHEMBL13963534 | 0.86 | ALDH1A1 (0.39) | CES1ALDH1A1TSHRHTTCYP3A4 | |
| SCHEMBL5574740 | 0.81 | CES1 (0.49) | CES1ALDH1A1CYP3A4SRCMAPT | |
| SCHEMBL1255415 | 0.81 | LMNA (0.50) | CES1ALDH1A1TSHRCYP3A4SRC | |
| SCHEMBL25375795 | 0.81 | CES1 (0.45) | CES1ALDH1A1TSHRHTTCYP3A4 | |
| SCHEMBL274928 | 0.80 | CES1 (0.56) | CES1ALDH1A1TSHRHTTCYP3A4 | |
| SCHEMBL36097 | 0.80 | CES1 (0.59) | CES1TSHRHTTSRCAKT1 | |
| SCHEMBL7945147 | 0.79 | CES1 (0.49) | CES1ALDH1A1TSHRCYP3A4SRC | |
| SCHEMBL10384389 | 0.78 | CYP3A4 (0.42) | CES1ALDH1A1TSHRCYP3A4SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |
| US-4144157-A | ACRYLIC ESTERS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |