Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6638708 | 0.91 | HTR1D (0.30) | ALDH1A1 | |
| SCHEMBL10879541 | 0.80 | ALOX5 (0.34) | — | |
| SCHEMBL10880421 | 0.80 | GAA (0.39) | — | |
| SCHEMBL10878250 | 0.79 | ADRA2A (0.31) | — | |
| SCHEMBL6640786 | 0.79 | MEN1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL11004812 | 0.78 | GAA (0.38) | — | |
| SCHEMBL5155419 | 0.77 | — | — | |
| SCHEMBL10864418 | 0.76 | — | — | |
| SCHEMBL10879537 | 0.76 | ACHE (0.30) | — | |
| SCHEMBL4716982 | 0.75 | PARP10 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030616-B1 | SUBSTITUTED 2-PHENYLAMINO-2-IMIDAZOLINES, THEIR ACID ADDITION SALTS, MEDICAMENTS CONTAINING THEM AND PROCESSES FOR PREPARING SAME | C.H. BOEHRINGER SOHN (DE) | 1984-01-11 | — | — | EP | claimed |
| EP-0051809-A1 | 7-(2,6-Dibromo-4-methylphenyl)-2,3-dihydroimidazo(1,2-a) imidazoles, their acid addition salts, medicines containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1982-05-19 | — | — | EP | claimed |
| EP-0030616-A1 | Substituted 2-phenylamino-2-imidazolines, their acid addition salts, medicaments containing them and processes for preparing same | C.H. BOEHRINGER SOHN (DE) | 1981-06-24 | — | — | EP | claimed |
| EP-0030616-B1 | SUBSTITUTED 2-PHENYLAMINO-2-IMIDAZOLINES, THEIR ACID ADDITION SALTS, MEDICAMENTS CONTAINING THEM AND PROCESSES FOR PREPARING SAME | C.H. BOEHRINGER SOHN (DE) | 1984-01-11 | — | — | EP | disclosed |
| US-4409235-A | BRADYCARDIACS | C. H. BOEHRINGER SOHN (DE) | 1983-10-11 | — | — | US | disclosed |
| EP-0051809-A1 | 7-(2,6-Dibromo-4-methylphenyl)-2,3-dihydroimidazo(1,2-a) imidazoles, their acid addition salts, medicines containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1982-05-19 | — | — | EP | disclosed |
| EP-0051809-A1 | 7-(2,6-Dibromo-4-methylphenyl)-2,3-dihydroimidazo(1,2-a) imidazoles, their acid addition salts, medicines containing them and processes for their preparation | C.H. BOEHRINGER SOHN (DE) | 1982-05-19 | — | — | EP | disclosed |
| EP-0030616-A1 | Substituted 2-phenylamino-2-imidazolines, their acid addition salts, medicaments containing them and processes for preparing same | C.H. BOEHRINGER SOHN (DE) | 1981-06-24 | — | — | EP | disclosed |
| EP-0030616-A1 | Substituted 2-phenylamino-2-imidazolines, their acid addition salts, medicaments containing them and processes for preparing same | C.H. BOEHRINGER SOHN (DE) | 1981-06-24 | — | — | EP | disclosed |