Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093498 | 0.86 | CYP2D6 (0.31) | CYP2D6DGAT1HDAC3HDAC1HDAC2 | |
| SCHEMBL19459343 | 0.78 | DGAT1 (0.38) | MEN1GAAKMT2ATDP1CYP2D6 | |
| SCHEMBL2765260 | 0.75 | DGAT1 (0.31) | MEN1GAAKMT2ADGAT1 | |
| SCHEMBL15109970 | 0.72 | LDHA (0.38) | — | |
| SCHEMBL11099153 | 0.71 | DGAT1 (0.34) | CYP2D6DGAT1 | |
| SCHEMBL21082018 | 0.71 | HMGCR (0.31) | CYP2D6 | |
| SCHEMBL241533 | 0.71 | DGAT1 (0.46) | MEN1GAAKMT2ATDP1CYP2D6 | |
| Acetic Acid SCHEMBL28025379 | 0.69 | DGAT1 (0.41) | MEN1GAAKMT2ATDP1CYP2D6 | |
| SCHEMBL52738 | 0.69 | MEN1 (0.42) | MEN1GAAKMT2ATDP1CYP2D6 | |
| Methyl Alcohol SCHEMBL27995686 | 0.69 | DGAT1 (0.44) | MEN1GAAKMT2ATDP1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427586-A | ANTI-BACTERIAL AGENTS AND ENZYME INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-01-24 | — | — | US | disclosed |