Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223525 | 0.97 | MEN1 (0.41) | MEN1GAAKMT2ADGAT1TDP1 | |
| SCHEMBL21406297 | 0.97 | MEN1 (0.41) | MEN1GAAKMT2ADGAT1TDP1 | |
| SCHEMBL28314694 | 0.97 | MEN1 (0.41) | MEN1GAAKMT2ADGAT1TDP1 | |
| Ammonia Solution, Strong SCHEMBL3971260 | 0.97 | MEN1 (0.41) | MEN1GAAKMT2ADGAT1TDP1 | |
| Ethane SCHEMBL1979252 | 0.97 | MEN1 (0.41) | MEN1GAAKMT2ADGAT1TDP1 | |
| SCHEMBL27486074 | 0.97 | MEN1 (0.41) | MEN1GAAKMT2ADGAT1TDP1 | |
| Methane SCHEMBL17763563 | 0.97 | MEN1 (0.41) | MEN1GAAKMT2ADGAT1TDP1 | |
| SCHEMBL28314719 | 0.95 | MEN1 (0.40) | MEN1GAAKMT2ADGAT1TDP1 | |
| Butane SCHEMBL14890902 | 0.93 | MEN1 (0.39) | MEN1GAAKMT2ADGAT1TDP1 | |
| SCHEMBL25275143 | 0.88 | DGAT1 (0.37) | MEN1GAAKMT2ADGAT1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735459-A1 | METHODS AND INTERMEDIATES FOR PREPARING ANTIVIRAL PRODRUGS | GILEAD SCIENCES, INC. (US) | 2026-05-06 | — | — | EP | claimed |
| CN-119639162-A | Anti-aging polyolefin material and preparation method thereof | 南京博科新材料产业研究院有限公司 | 2025-03-18 | — | — | CN | claimed |
| WO-2025050033-A1 | SECONDARY FUEL GENERATING COMPLEXING AGENTS FOR ULTRA-LOW TEMPERATURE METAL COMPOUND FORMATION VIA COMBUSTION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-03-06 | — | — | WO | claimed |
| WO-2025006582-A1 | METHODS AND INTERMEDIATES FOR PREPARING ANTIVIRAL PRODRUGS | GILEAD SCIENCES, INC. (US) | 2025-01-02 | — | — | WO | claimed |
| CN-118791713-A | Polyester resin, solvent-free adhesive, preparation method of solvent-free adhesive, aluminum plastic film and lithium battery | 苏州瀚海新材料有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118598749-A | Photosensitive functionalized metal carboxylate and photosensitive nanocrystalline composite material prepared by same | 河北工业大学 | 2024-09-06 | — | — | CN | claimed |
| CN-118206612-A | Ocotill type sapogenin A cycloaminothiazole ring derivative and preparation method and application thereof | 烟台大学 | 2024-06-18 | — | — | CN | claimed |
| EP-4368686-A1 | LUBRICITY IMPROVER COMPOSITION FOR FUEL OIL AND USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2024-05-15 | — | — | EP | claimed |
| CN-114605622-B | Aliphatic polyester with malonic acid structure, and preparation method and application thereof | 苏州瀚海新材料有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117700654-A | Copolyester for weather-resistant coating and preparation method and application thereof | 中瀚新材料科技有限公司 | 2024-03-15 | — | — | CN | claimed |
| US-20090012304-A1 | preparation of intermediates 3-[3-(4-methyl-5-methylsulfanyl-4H-[1,2,4]triazol-3-ylmethyl)phenoxy]-5-difluoromethyl-benzonitrile derivatives; for making enzyme inhibitors of HIV-1 reverse transcriptase, treating AIDS and HIV-1 syndromes | ROCHE PALO ALTO LLC | 2009-01-08 | — | — | US | claimed |
| WO-2008145563-A2 | PROCESS FOR PREPARING TRIAZOLONES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-04 | — | — | WO | claimed |
| US-7193090-B2 | Preparation of atorvastatin | APOTEX PHARMACHEM INC. (CA) | 2007-03-20 | — | — | US | claimed |
| EP-1725527-A1 | AN IMPROVED PREPARATION OF ATORVASTATIN | Apotex Pharmachem Inc. (CA) | 2006-11-29 | — | — | EP | claimed |
| WO-2005087723-A1 | AN IMPROVED PREPARATION OF ATORVASTATIN | APOTEX PHARMACHEM INC. (CA) | 2005-09-22 | — | — | WO | claimed |
| US-20050203302-A1 | Preparation of atorvastatin | APOTEX PHARMACHEM INC. | 2005-09-15 | — | — | US | claimed |
| US-6913865-B2 | Surface modified encapsulated inorganic resist | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-07-05 | — | — | US | claimed |
| US-20030099897-A1 | Surface modified encapsulated inorganic resist | MASS INSTITUTE OF TECHNOLOGY (MIT) | 2003-05-29 | — | — | US | claimed |
| US-6004823-A | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-21 | — | — | US | claimed |
| US-4189583-A | FROM 1-METHYL-2-OXO-3-METHYLENE-4-(3'-METHOXYPHENYL)-4 -(CARBOXYMETHYLENE)PIPERIDINE BY CYCLIZATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1980-02-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203302-A1 | Preparation of atorvastatin | HMGCR, CYP7A1, FAR1 | MEN1 3366/4885GAA 1169/4885KMT2A 2235/4885 |
| US-20090012304-A1 | preparation of intermediates 3-[3-(4-methyl-5-methylsulfanyl-4H-[1,2,4]triazol-3-ylmethyl)phenoxy]-5-difluoromethyl-benzonitrile derivatives; for making enzyme inhibitors of HIV-1 reverse transcriptase, treating AIDS and HIV-1 syndromes | POLRMT, TYMS, POLR1G | MEN1 4182/4885GAA 744/4885KMT2A 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.